School District #37 was created as a small district to save the village of Gretna in 1888. The first school to serve Gretna children was located across the road from the LaBorde cemetery outside Gretna. A two-story brick schoolhouse was constructed in 1898 south of Angus Street across from St. Patrick's Catholic Church. Its size was doubled in 1908, and a gymnasium was added in 1936.
As the village grew, so too did the school district. Through minor consolidation over the years and a major consolidation in 1958, the district has grown to its present size of 70 square miles.